Outlook Anywhere is one of the very popular features in Exchange Server 2007. It allows Outlook 2007 and Outlook 2003 clients to connect to Exchange Server over the Internet by using RPC (Remote Procedure Calls) over HTTP.
1) Install Certificate Authority
2) Install RPC over http from Control Panel
3) Confirm you have 2 virtual directories installed called RPC and RPC with Cert
Check IIS if RPC and RPCWithCert directory exists under default website.
Check IIS if RPC and RPCWithCert directory exists under default website.
4) Also check Website Extension consists RPC Proxy server.
5) Enable Outlook Anywhere from Exchange Console.
6) Check if registry consists of proper port numbers.
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